Trimethylglycine. Betaine — also called betaine anhydrous, or trimethylglycine (TMG) — is a substance that’s made in the body. It’s involved in liver function, cellular reproduction, and helping make carnitine. It also helps the body metabolize an amino acid called homocysteine.
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What is Trimethylglycine used for?
TMG has been studied for many potential health benefits, including the ability to enhance heart health, boost athletic performance, promote healthy insulin levels, and protect against depression. However, it may also cause side effects, especially if used in high doses.
What does betaine anhydrous do for the body?
Betaine anhydrous helps in the metabolism of a chemical called homocysteine. Homocysteine is involved in the normal function of many different parts of the body, including blood, bones, eyes, heart, muscles, nerves, and the brain. Betaine anhydrous prevents the buildup of homocysteine in the blood.
When should I take betaine anhydrous?
When Should I Take Betaine? Betaine can be taken daily as a pre or post workout supplement. Research shows a hefty amount of betaine is lost in sweat during a workout, so it would be smart to refuel after an especially difficult workout session. We recommend 1.25 – 1.5 grams, twice a day.
How long does it take for TMG to work?
Many studies were 10-15 days in nature, demonstrating the potential for rapid benefits. One of the most recent studies in 2013 was 6 weeks long and showed that longer term TMG supplementation improved body composition, arm size, muscle power output and bench press work capacity.
When is the best time to take TMG?
Take two (2) capsules in the morning with or without food, or as recommended by a healthcare practitioner. TMG should be taken with co-factors B6, B12, and folic acid. If muscle tension or headaches occur, reduce the dose or discontinue product, and inform your physician if they do not subside.
Is trimethylglycine good for the liver?
In the liver, TMG helps process methionine to produce S-adenosylmethionine, which helps lower inflammation. It can also help decrease liver cell death [21, 31]. In mice, TMG improved liver health by: Decreasing insulin resistance in the liver [21]
Is betaine good for the liver?
In humans, dietary betaine was found to improve liver function in fatty liver disease, including steatohepatitis [43,48,58,59]. In animals and cultured cells, betaine had protective effects against liver injury, but the mechanism has not been determined [45,60].
Does betaine anhydrous cause hair loss?
Other adverse reactions include: anorexia, agitation, depression, irritability, personality disorder, sleep disturbed, dental disorders, diarrhea, glossitis, nausea, stomach discomfort, vomiting, hair loss, hives, skin odor abnormalities, and urinary incontinence.
Does betaine anhydrous boost testosterone?
Betaine supplementation increased testosterone levels and T/C ratio in youth professional soccer players during a competitive season. Betaine supplementation had no negative effects on growth (height and weight) and may attenuate reductions in testosterone due to intense training during puberty.
Does betaine make you gain weight?
The results showed that supplemental betaine significantly reduced the total body fat mass and percentage in humans, but it had no significant effects on body weight and BMI.
Is betaine good for kidneys?
Betaine reduces serum uric acid levels and improves kidney function in hyperuricemic mice. Planta Med.
Is betaine anhydrous better than creatine?
Betaine And Creatine Betaine is often compared to creatine. One reason is that both creatine and betaine improve power as well as strength. As we will see in the Heart Health section, betaine reduces levels of homocysteine. It does this by converting it to methionine.
Is betaine worth taking?
Recent studies on betaine, also known as trimethylglycine, suggest that betaine supplementation can improve power output and physical endurance. However, researchers note that this effect is unreliable. Betaine does provide benefits for physical performance after supplementation.
What foods contain trimethylglycine?
TMG is obtainable from foods such as wheat bran, wheat germ, spinach, and beets. It can also be synthesized in the body from choline (Millian and Garrow, 1998).
Does TMG cause anxiety?
People who are experiencing overmethylation are generally very anxious. This is because overmethylation can create high levels of dopamine, norepinephrine, and epinephrine in the brain.
Does TMG give you energy?
Apart from its basic roles, TMG has also been studied for its potential effects on physical performance, power output, energy, and muscle growth. These effects have made TMG a trendy ingredient in many gym supplements, often included in the form of betaine anhydrous.
Is TMG better than DMG?
TMG is also an osmolyte, a substance that has protective qualities and stabilizes proteins. Since DMG is neutral, it crosses the blood-brain barrier easier. In other words, you might get both substances into your system, but DMG is transferred more effectively than TMG.
Does betaine raise cholesterol?
Conclusions: Betaine supplementation increased blood LDL cholesterol and triacylglycerol concentrations in healthy humans, which agrees with the limited previous data. The adverse effects on blood lipids may undo the potential benefits for cardiovascular health of betaine supplementation through homocysteine lowering.
Does TMG increase stomach acid?
TMG supplements alleviate the body’s need for methyl donors, which may benefit people deficient in methyl donors. In the form of betaine HCl, it is sometimes used to increase stomach acid, although this use is questionable.
How long does TMG last?
In the majority of cases, TMJ syndrome is self-limiting. Most of the symptoms disappear in two weeks once the jaw is rested There are a variety of options for treating TMJ syndrome at home. Anti-inflammatory and pain medications such as aspirin or acetaminophen (Tylenol) or ibuprofen (Motrin, Advil) may provide relief.
Does betaine anhydrous lower blood pressure?
Betaine serves as a methyl donor in a reaction converting homocysteine to methaionine. Previous studies showed, equivocally, that betaine could reduce blood pressure (bp) and blood homocysteine level.
Which foods contain betaine?
Humans obtain betaine from foods that either contain betaine or choline. Betaine is rich in foods, such as wheat bran, wheat germ, spinach, beets, and whole grains, although exact values will vary with different sources of foods and cooking methods.
Is trimethylglycine the same as betaine HCl?
It is known as a “betaine” molecule (“betaine” being a category of molecules), but because it was the first dietary betaine discovered (from beetroot) and is the most popular molecule referred to as a betaine, the terms “trimethylglycine” and “betaine” are used interchangeably.
How much betaine is safe?
Adults, teenagers, and children 3 years of age and older—The starting dose is usually 3 grams taken two times a day with meals. Your doctor may adjust your dose as needed. Children younger than 3 years of age—The dose is based on body weight and must be determined by your doctor. Betaine should be taken with meals.